Hey @Jared_Huet. Welcome to our community! You can definitely do a 2x2 configuration for 4 - 4k touchscreens so long as your PC supports it. You can find general requirements in our installation documentation linked above. You will also need to update the local.cfg file to configure the 4 displays. This Mosaic Setup guide should be useful for you to configure this.
Please reach out if you have additional questions!